Editorial endogamy in some Latin American dental journals

Objective: Scientific publication in a journal by a member of the editorial committee of the same journal is known as authorial endogamy. To determine the presence of authorial endogamy in some Latin American dental journals. Material and Methods: Observational, descriptive, retrospective study. Eight dental journals from Brazil, Cuba and Chile indexed to Scopus in the period of 2018 - 2021 were analyzed. An evaluation was made of the manuscripts that include a member of the editorial committee as author. The results were expressed in percentages and frequency measurements and for the bivariate analysis, the Mann-Whitney U test and Fisher's exact test were used (p<0.05). Results: A total of 2026 articles, from which 14.52% (n=256), of authorial endogamy were found. The endogamy articles were mostly original articles 98.05% (n=252), experimental design 39.70% (n=102), advisory council 49.36% (n=153), co-authorship position 58.97% (n=184), with presence of 1 endogamic author per article 82.94% (n=214), the number of days from submission to acceptance were statistically lower in endogamic articles (p=0.003). Conclusion: The presence of editorial endogamy in some dental journals in Latin America was low, this finding is more frequent in original articles, mostly from the advisory board and as co-author. Additionally; it was found that endogamic articles took less days in editorial process. (AU)

Objetivo: A publicação científica em uma revista por um membro do comitê editorial da mesma revista é conhecido como endogamia autoral. Determinar a presença de endogamia autoral em algumas revistas odontológicas na América Latina. Material e Métodos: Estudo retrospectivo observacional e descritivo. Oito revistas odontológicas do Brasil, Cuba e Chile, indexadas na Scopus no período entre 2018 - 2021 foram analisadas. Foi realizada uma avaliação dos artigos que incluíam autores membros do comitê editorial. Os resultados foram expressos em porcentagem e medidas de frequência, e para a análise de bivariância foram utilizados o teste de Mann-Whitney U e teste exato de Fisher (p<0,05). Resultados: Foi um total de 2026 artigos, entre os quais 14,52% (n=256) foram detectados endogamia autoral. Os artigos endogâmicos foram, em sua maioria, artigos originais 98,05% (n=252), desenho experimental 39,70% (n=102), conselho consultivo 49,36% (n=153), em posição de co-autoria 58,97% (n=184), com a presença de 1 autor endogâmico por autor 82,94% (n=214), e o número de dias desde a submissão até o aceite foram estatisticamente menores em artigos endogâmicos (p=0,003). Conclusão: A presença de endogamia editorial em algumas revistas odontológicas na América Latina foi baixa, sendo este achado mais frequente em artigos originais, predominantemente em conselho consultivo e como co-autor. Adicionalmente, foi observado que artigos endogâmicos levaram menos dias no processo editorial (AU)

¿Aislamiento social preventivo, o aislamiento endogámico? Acerca de sus efectos en los trabajos psíquicos de una adolescente durante la pandemia / Preventive lockdown or endogamous lockdown? Its effects on the psychic work of anadolescent during the pandemic / Isolement social préventif ou isolement consanguin? Sur ses effets sur le travail psychique d'unadolescent pendant la pandémie / Isolamento social preventivo ou isolamento endogâmico? Reflexões sobre seus efeitos no atendimento psicoterápico com uma adolescente durante a pandemia

La pandemia por COVID-19 llevó a un nuevo orden mundial. El afuera se convirtió en un espacio vedado, la premisa principal fue la convivencia absoluta con una familia o la soledad del hogar, aparecieron el temor al contagio y la muerte que nos comunicaban a diario. El aislamiento como condición llevó a la virtualidad como posibilidad de conectarnos con otros, de explorar desde dentro y de sobrellevar de algún modo el encierro. La virtualidad como dispositivo de encuentro atravesó todas las áreas, incluida la salud, mediante la teleconsulta o videollamada se sostuvieron los tratamientos o bien se iniciaron otros. En el presente trabajo se analizarán las sesiones virtuales con una joven que llega a tratamiento psicoanalítico por pedido de su madre, con el fin de entrecruzar la sintomatología que permite la apertura de una demanda propia y los trabajos psíquicos adolescentes desde el interior de su cuarto AU

The COVID-19 pandemic led to a new world order. The outside became a barred territory and the main premise was full-time coexistence with all the household members or a life in the solitude of the household. The fear of contagion and death appeared as a result of daily reports. Isolation as a condition led to virtual communication as a way to connect with others, to explore from the inside and somehow endure lockdown. The virtual realm as a meeting point was used across all areas, including healthcare ⎯oldtreatments continued and new treatments started through teleconsultations or video calls. The present paper analyzes the virtual sessions of a young girl starting psychoanalytic treatment at the request of her mother in order to intertwine the symptoms enabling a personal demand and adolescent psychic work from inside her room AU

La pandémie de COVID-19 a conduit à un nouvel ordre mondial. L'extérieur se convertit en un espace clos, la prémisse principale devenait la coexistence absolue avec une famille ou la solitude du foyer, laissant apparaitre quotidiennement la peur de la contagion et de la mort. L'isolement en tant que condition a conduit à la virtualité en tant quepossibilité de se connecter aux autres, d'explorer de l'intérieur et de faire face d'une manière ou d'une autre à l'enfermement. La virtualité comme dispositif de rencontre traversait tous les domaines, y compris celui de la santé : grâce à la téléconsultation ou à l'appel vidéo, certains traitements pouvaient être maintenus tandis que d'autres modalités pouvaient apparaitre.Dans le présent travail, les séances virtuelles avec une jeune femme qui vient en cure psychanalytique à la demande de sa mère seront analysées, afin de croiser la symptomatologie que permet l'ouverture de son propre processus et le travail psychique adolescent depuis l'intérieur de sa chambre AU

A pandemia da COVID-19 levou a uma nova ordem mundial. A vida externa virou espaço proibido, a prioridade principal foi a convivência absoluta com a família ou a solidão da casa. Aparecerem o temor ao contágio e a morte que nos comunicavam diariamente. O isolamento como condição fez com que a virtualidade se tornasse possibilidade de conectarmos com os outros, de explorarmos a vida a partir de dentro e de suportarmos de algum modo o fato de estarmos isolados. O envolvimento virtual por meio de plataformas de comunicação digital abrangeu todas as áreas, incluindo a saúde: mediante as consultas online e as vídeos chamadas, alguns continuaram os tratamentos, outros iniciaram naquele novo formato. No presente trabalho são analisadas as sessões virtuais com uma adolescente que iniciou o tratamento psicanalítico a pedido de sua mãe, entrelaçando a sintomatologia que permite a abertura de uma demanda própria e os trabalhos psíquicos adolescentes desde o interior de seu quarto AU

Pattern of Hemoglobinopathy among the Young Tribes of West Bengal: A Completely Different Scenario from Rest of India

Hemoglobinopathy is a major concern among the tribal population which constitutes 8.6% of the total population, and West Bengal (WB) is the home to 5.3 million tribes. The present study was conducted on 52,880 tribal school students from all the districts of WB. Written informed consent and peripheral blood were collected for complete blood count and high‑performance liquid chromatography analysis. Beta trait was 5.3%, sickle trait was 2.35%, and hemoglobin (Hb) E (HbE) trait was 1.4% in this population. About 37.8% of beta trait belonged to the Santal tribe and 21.5% belonged to Oraon. HbS is mainly found in Alipurduar and Jalpaiguri districts at the prevalence of 3.69% and 5.96%, respectively. HbE trait is found at 6.06% in Alipurduar, of which 51% of cases are from Mech tribe only found in this district. Unlike central and Western parts of India, HbS trait in WB was significantly low among the tribes. A high prevalence of consanguinity among the tribes is considered responsible for the high rate of hemoglobinopathy.

La endogamia como causa de consanguinidad y su asociación con anomalías congénitas / Endogamy as a cause of consanguinity and its association with congenital anomalies

El papel de la endogamia como causa de homocigosidad en la salud humana es un foco de interés en genética médica, debido a su relación con anomalías congénitas y patologías genéticas recesivas. Es un tema importante a pesar de que las tasas de uniones consanguíneas en ciertas sociedades han disminuido con el tiempo; sin embargo, en algunas comunidades se han mantenido estables o han aumentado. La consanguinidad es practicada hasta en el 10% de la población mundial, y los motivos más comúnmente citados son socioculturales y socioeconómicos. Aunque se ha visto una disminución de esta práctica, probablemente por la migración urbana y el aumento de las tasas de educación, la consanguinidad continúa practicándose en todo el mundo. Los efectos más significativos sobre los resultados reproductivos se deben, principalmente, a condiciones hereditarias autosómicas recesivas, que también aumentan la frecuencia de algunos desórdenes médicos. El objetivo de esta revisión es dar a conocer la epidemiología y los factores predisponentes de la consanguinidad, así como presentar la evidencia actual de la asociación entre la consanguinidad originada en la endogamia y las anormalidades congénitas y patologías médicas como consecuencia de trastornos genéticos mendelianos. Se requiere un enfoque culturalmente apropiado para el asesoramiento genético en relación con la endogamia

The role of consanguinity as a cause of homozygosity in human health is a focus of interest in medical genetics, due to its relationship with congenital anomalies and recessive genetic pathologies. This is an important issue since the rates of consanguineous unions in certain societies have decreased over time, but have remained stable or have increased in others. Consanguinity is practiced in up to 10% of the world population, and the most common reasons are sociocultural and socioeconomic factors. Although there has been a decrease in this practice, probably due to urban migration and an increase in education rates, consanguinity continues to be practiced throughout the world. The most significant effects on reproductive outcomes are mainly due to autosomal recessive hereditary conditions, that also increase the frequency of medical disorders. The aim of this review is to present the current evidence of the association between consanguinity originating from endogamy, with congenital abnormalities and medical disorders originated from mendelian genetic pathologies. A cultural appropriate approach is required for genetic counseling in relation to consanguineous endogamy

Contested domains of biological similarities and sociocultural diversity

Scientists and social scientists often read the same text differently. They also construct categories having the samenomenclature independently. Many of us also work in isolated domains, rarely reading texts researched and documented byothers. We conduct our research within the defined format of our disciplines. We engage with others only when contestations emerge and challenge some of the rooted paradigms of each other’s disciplines. This paper reflects the reactions of asocial scientist to texts on population genetics and attempts to arrive at the genetic theory of the origin of ethnologicalhistory of human populations in India. Inadvertently, most of these intensely researched and passionately documented DNAevidence present a serious challenge to the discourse of cultural pluralism and social diversity that the humanist perspectiveof science and social science takes pride in documenting. This paper is based on secondary resource materials and themethodology adopted is that of narrative research.

Intrapopulational genic variation of the giant African Snail (Achatina fulica) in the Valle del Cauca / Variación génica intrapoblacional del caracol gigante africano (Achatina fulica) en el Valle del Cauca

ABSTRACT Objective. To evaluate the intrapopulation genetic variation of A. fulica in the Valle del Cauca. Materials and methods. Ten microsatellite loci from specimens collected at eight municipalities in the Valle del Cauca Department were amplified. Allelic frequencies and descriptors of intrapopulation genetic diversity were estimated. Bayesian analysis was used to estimate the number of groups present in the study area. Results. Two groups were identified in the Valle del Cauca (p > 50%): one group comprised individuals from the north and center of the department, and one group comprised individuals from the south and west of the department. These groups were genetically different from each other (FST 0.16; p<0.05). Isolation by distance was confirmed (Mantel p 0.01; R2 0.06), and a high level of endogamy was detected through a deficit of heterozygotes in the evaluated loci (FIS 0.45). Conclusions. We suggest that the A. fulica population present in the Valle del Cauca could have been introduced at more than one location, or that there could have been more than one wave of invasion. The high level of endogamy is probably the result of control activities that eliminated adult individuals in the population, which has led to an enhanced founder effect.

RESUMEN Objetivo. Evaluar la variación genética intrapoblacional de A. fulica en el Valle del Cauca. Materiales y métodos. Se amplificaron diez loci microsatélites de muestras obtenidas en ocho municipios del Departamento. Se estimaron las frecuencias alélicas y descriptores de la diversidad genética intrapoblacional y se discriminó mediante un análisis bayesiano la cantidad de agrupaciones presentes en la zona de estudio. Resultados. Se identificaron dos agrupaciones en el Valle del Cauca (p>50%): una conformada por los individuos de los municipios del Norte y Centro, otra por los municipios del Sur y Occidente. Estas agrupaciones, fueron genéticamente diferentes (FST0.16; p<0.05), confirmándose además aislamiento por distancia (Mantel p 0.01; R20.06) y un alto nivel de endogamia a partir del déficit de heterocigotos en los loci evaluados (FIS0.45). Conclusiones. Se sugiere que la población de A. fúlica en el Valle del Cauca pudo tener más de un lugar de introducción o incluso más de una oleada de invasión. Además, el alto nivel de endogamia probablemente es el resultado de las actividades de control, las cuales eliminan individuos adultos de la población lo que conlleva al incremento de la deriva per se del efecto fundador.

Genetic diversity of Arapaima gigas (Schinz, 1822) (Osteoglossiformes: Arapaimidae) in the Araguaia-Tocantins basin estimated by ISSR marker

The genetic diversity of the specimens of four natural populations of Arapaima from Araguaia-Tocantins basin was assessed within and among these stocks, using five primers for ISSR. COI (cytochrome c oxidase subunit I) partial sequences confirmed that the specimens belongs to Arapaima gigas. The ISSR provided 168 loci, of which 165 were polymorphic. However, the number of loci for each population and expected heterozygosity values were low. AMOVA showed 52.63% intra-population variation and 47.37% inter-population variation. The F ST was high among all populations (F ST ≥ 0.25), however, the cluster analysis (PCoA) and Bayesian inference showed three major groups: Araguaiana-MT + São Félix do Araguaia-MT, Novo Santo Antônio-MT and Itupiranga-PA. The genetic distance was not correlated with geographical distance. The ISSR marker revealed that the populations of the Araguaia-Tocantins are structured and have a low genetic diversity. These are the first data from a population analysis using molecular markers for A. gigas of Araguaia-Tocantins basins and may be used to define the best management strategies and conservation projects for this species.

A diversidade genética dos espécimes de quatro populações naturais de Arapaima coletados na bacia do Araguaia-Tocantins foi avaliada com base em cinco primers para marcadores moleculares ISSR. A sequência parcial do COI (cytochrome c oxidase subunit I) confirmou que os espécimes pertencem à espécie Arapaima gigas. Os ISSR forneceram 168 loci, dos quais 165 polimórficos. No entanto, para cada população, os valores de heterozigosidade esperada foram baixos. A AMOVA mostrou 52,63% de variação intrapopulacional e 47,37% interpopulacional. O F ST foi alto entre todas as populações (F ST ≥ 0,25); entretanto, a análise de agrupamento e a inferência Bayesiana mostraram três grandes grupos: Araguaiana-MT + São Félix do Araguaia-MT, Novo Santo Antônio-MT e Itupiranga-PA. A distância genética não teve correlação com a distância geográfica. Os ISSRs se mostraram eficientes para determinar a diversidade genética para a A. gigas, revelando que as populações da bacia Araguaia-Tocantins estão estruturadas e com baixa diversidade genética. Estes são os primeiros dados de análise populacional utilizando ISSR para A. gigas da bacia Araguaia-Tocantins e poderão ser utilizados para definir as melhores estratégias de manejo e projetos de conservação dessa espécie.

A endogamia explicaria a elevada prevalência de deficiências em populações do Nordeste brasileiro? / Could endogamy explain the higher prevalence of disabilities in the population of the Brazilian Northeast?

Apesar da inexatidão conceitual e de métodos de aferição, a OMS estima que cerca de 10% da população mundial apresente alguma forma de deficiência. Com a finalidade de investigar a prevalência e a etiologia das deficiências e verificar se elas estariam associadas à endogamia, foi realizado um estudo epidemiológico transversal com uso do método do informante envolvendo cinco municípios do Estado do Rio Grande do Norte, no Nordeste brasileiro; nos quais foram estimadas frequências de casamentos consanguíneos que variam de 9 a 32%. A prevalência média estimada para deficiências nos cinco municípios amostrados foi de 4,53%, obtida por meio de entrevistas envolvendo 37,87% de uma população de 39.054 habitantes. Em média, 25% dos casais consanguíneos e 12% dos não consanguíneos apresentaram um ou mais filhos com alguma deficiência. A elevada prevalência de pessoas com deficiência no Nordeste brasileiro pode ter associação com a manutenção da tradição de casamentos consanguíneos nessas populações e parte dessas deficiências pode ser causada por doenças genéticas.

Despite conceptual inaccuracies and methods of measurement, the WHO estimates that about 10% of the world population has some form of disability. In order to investigate the prevalence and etiology of disabilities and to evaluate if they could be associated with inbreeding, a cross-sectional epidemiological study was conducted using the informant method in five communities of the state Rio Grande do Norte in the Brazilian Northeast, in which consanguineous marriages frequencies varied between 9 and 32%. The average prevalence of disabilities in the five sampled communities was 4.53%, obtained by interviews that involved 37.87% of a population of 39,054 inhabitants. On average, 25% of consanguineous and 12% of non-consanguineous couples had one or more children with disabilities. The increased rate of individuals with disabilities in the Brazilian Northeast could be associated with the maintenance of the tradition of consanguineous marriages in these populations and some of these disabilities may be caused by genetic disorders.

Inbreeding in sugarcane varieties / Autofecundação em variedades de cana-de-açúcar

Sugarcane species are allogamous, i.e. selfing is expected to reduce plant vigor. This study was undertaken to obtain and evaluate first-generation inbred lines that may be used for further crosses and determine the extent of inbreeding depression in sugarcane. In this research, 26 parental varieties were self-pollinated to obtain about 19,000 seedlings. Results showed that it is possible to segregate different traits in a given variety and find lines with promising outcome for all assessed characteristics. The soluble solids segregation observed in low and even high-Brix varieties increases the possibility of quick improvement in this trait. Self-pollination did not produce a general loss in yield traits such as soluble solids, stalk number and stalk diameter in any of the 26 varieties, but both stalk height and stalk weight showed strong inbreeding depression. Selfing-derived clones can be used to produce hybrid vigor in crossings.

Cana-de-açúcar tem sido considerada como uma planta alógama e, por esta razão, a autofecundação deveria produzir uma redução no vigor das plantas. O objetivo deste estudo foi obter e avaliar a primeira geração de linhas autofecundadas que podem ser usadas em mais cruzamentos e também determinar a extensão da depressão causada por essa autofecundação em cana-de-açúcar. Neste trabalho, 26 variedades utilizadas como parentais foram autofecundadas, das quais se obtiveram cerca de 19.000 plântulas. Os resultados mostraram que é possível segregar diferentes características em uma dada variedade sem perder vigor e encontrar progênies com características superiores. A segregação observada para Brix por cento em variedades de baixo, e até mesmo nas de alto Brix, aumenta a possibilidade de melhoramento dessa característica. Autofecundação não produziu uma perda geral nos atributos de produção nas 26 variedades estudadas, mas a altura e massa de colmos apresentaram forte depressão por endogamia. Clones derivados de autofecundação podem ser usados para produzir vigor híbrido nos cruzamentos.

Somatic development and embryo yield in crossbred F1 mice generated by different mating strategies / Desenvolvimento somático e produção de embriões em camundongos cruzados F1 gerados com diferentes estratégias de cruzamento

The aim of this study was to evaluate different mating strategies among endogamic strains to create F1 populations of mice, minimising the effect of inbreeding depression on somatic development and embryo yield. Females from the strains Swiss, CBA and C57Bl/6 were divided in nine experimental mate arrangements. The total numbers of pups born alive per dam and somatic development, estimated by weighing and measuring the crown-rump length, were recorded. Superovulation response was evaluated in outbreed females. Litter size differed among endogamic dams, irrespective of the sire. Somatic development results suggest heterosis and imprinting phenomena, once a differential parental effect was demonstrated. There was no difference in corpora lutea, ova or embryos recovered (P > 0.05), but recovery and viability rates differ among F1 groups (P < 0.05). The association of dam prolificity with somatic development and superovulation response of the pups should be considered for experimental F1 populations establishment. The use of outbreed animals, however, did not reduce response variability to hormone treatment.

Objetivou-se neste estudo avaliar diferentes estratégias de cruzamento entre linhagens endogâmicas para a formação de populações de camundongos F1, minimizando o efeito da depressão por endogamia nos resultados de desenvolvimento somático e produção de embriões. Fêmeas das linhagens Swiss, CBA e C57Bl/6, foram distribuídas em nove possíveis cruzamentos. Foram registrados o número de filhotes nascidos vivos por matriz e o desenvolvimento somático dos mesmos, mensurado pelo peso e comprimento. A resposta superovulatória foi avaliada nas fêmeas cruzadas. O tamanho das ninhadas diferiu entre as linhagens das matrizes, de forma independente da linhagem dos reprodutores. Os resultados do desenvolvimento somático sugerem a ocorrência de heterose e imprinting, uma vez que foi demonstrado um efeito parental diferenciado. Não foram observadas diferenças no número de corpos lúteos, estruturas ou embriões recuperados (P > 0,05), mas as taxas de recuperação e o percentual de embriões viáveis diferiram entre os grupos (P < 0,05). A associação da prolificidade da linhagem das matrizes com as características do desenvolvimento somático e resposta superovulatória dos filhotes deve ser considerada no estabelecimento de populações experimentais F1. O uso de animais cruzados, contudo, não reduziu a variabilidade da resposta aos tratamentos hormonais.

Is the Central Valley of Costa Rica a genetic isolate?: [review]

In the last decade, the Costa Rican Central Valley population (CRCV), has received considerable scientific attention, attributed in part to a particularly interesting population structure. Two different and contradictory explanations have emerged: (1) An European-Amerindian-African admixed population, with some regional genetic heterocigosity and moderate degrees of consanguinity, similar to other Latin-American populations. (2) A genetic isolate, with a recent founder effect of European origin, genetically homogeneous, with a high intermarriage rate, and with a high degree of consanguinity. Extensive civil and religious documentation, since the settlement of the current population, allows wide genealogy and isonymy studies useful in the analysis of both hypotheses. This paper reviews temporal and spatial aspects of endogamy and consanguinity in the CRCV as a key to understand population history. The average inbreeding coefficients (a) between 1860 and 1969 show a general decrease within time. The consanguinity in the CRCV population is not homogeneous, and it is related to a variable geographic pattern. Results indicate that the endogamy frequencies are high but in general it was not correlated with a values. The general tendency shows a consanguinity decrease in time, and from rural to urban communities, repeating the tendencies observed in other countries with the same degree of development, and follows the general Western World tendency. Few human areas or communities in the world can be considered true genetic isolates. As shown, during last century, the CRCV population has had consanguinity values that definitively do not match those of true genetic isolates. A clear knowledge of the Costa Rican population genetic structure is needed to explain the origin of genetic diseases and its implications to the health system.

The impact of consanguinity on the Indian population.

Numerous studies have been conducted by Indian anthropologists into the prevalence of both consanguineous and affinal marriage.1-3 and the topic of consanguinity continues to attract great attention among geneticists and social scientists. The strengthening of family relationships is of primary importance in the preference for close kin unions, with economic benefits an additional consideration. Consanguinity does not appear to adversely affect human fertility. However, both postnatal morbidity and mortality are increased, with greatest effect so far observed in the early years of life. With declining mortality and morbidity due to infectious disease, recessive genetic disorders will progressively gain greater prominence in the overall spectrum of ill-health. This change will be especially obvious in communities which practise consanguineous marriage, and in small highly endogamous communities where random drift occurs.